内容医学免疫学23prophylaxis.pptxVIP

Immune prophylaxis and Immunotherapy;Immunoprophylaxis ;I. Introduction ; Variolation Vaccination; Variola minor.Somalia April 1977 ;Ways of acquiring specific immunity;II. Essential requirements of vaccine;5月1日，山东济宁市，疫苗不良反应受害者家庭的一次聚会中，孩子们在麦田里拍下了这张合影。据统计，中国每年疫苗预防接种达10亿剂次。这是个惊人的数字，意味着每年要有超过1000个孩子患上各种疫苗后遗症，留下终身残疾;III. Immunoprophylaxis;Agents used in active immunization ;Agents used in active immunization;Viruses are traditionally attenuated by selecting for growth in nonhuman cells;Viruses are traditionally attenuated by selecting for growth in nonhuman cells;Examples of live vaccines;Live attenuated vs inactivated Vaccines;Jonas Salk;3. Toxoid;4, Subunit vaccine These vaccines are in use which make use of antigens either purified from microorganisms or produced by binant DNA technology. e.g. HBV vaccine (HBsAg) ; 5, Conjugate vaccine; 6,DNA vaccine; 7,Genetic engineering vaccine; 8,Synthetic peptide vaccine; Transgenic plant vaccine;New Vaccines;Preventative Vaccine;Therapeutic Vaccine;Reverse vaccinology for identification novel vaccine antigen;Adjuvant;Application of Vaccines;Planned immunization schedule in China;Application of vaccines;Application of vaccines;Immunotherapy;Conception of immunotherapy Immunotherapy is the approach to balance or intervene the immunologic function in order to fight against the disease by the principle of immunology.;B, Classification of Immunotherapy;II. Molecular Immunotherapy;II. Molecular Immunotherapy;II. Molecular Immunotherapy ;Application of Ab in vitro: elimination of cancer cells in bone marrow or T cells to prevention GVHD;Monoclonal antibodies that recognize tumor-specific antigens might be used in a variety of ways to help eliminate tumors.;Examples of tumor antigens that have been targeted by monoclonal antibodies in therapeutic trials.;II. Molecular Immunotherapy ;II. Molecular Immunotherapy ;II. Molecular Immunotherapy ;III. Cellular Immunotherapy ;III.