2.2大二下2.病原生物学-8enterovirus.pptxVIP

27. ENTEROVIRUS GASTROINTESTINAL VIRUSES肠道病毒 和急性胃肠炎病毒;教学大纲;Objectives;Belong to the family Picornaviridae (小RNA病毒科) Include Polioviruses 脊髓灰质炎病毒 Coxsackieviruses 柯萨奇病毒 ECHO viruses 埃可病毒 Enterovirus 68-71+ 新肠道病毒 68-71+型 ;Properties of enteroviruses;Transmission;;? Poliovirus is an important model: - first virus purified and crystallized. - first inactivated vaccine used (Salk 1950’s). - first picornavirus to be sequenced. - first infectious cDNA clone of an animal virus. - first picornavirus structure to be solved. ;;Poliovirus ;Clinical findings; ;Iron lung ward in the 1950s ;Geograph