斯坦福分子生物学讲义dnai.pptxVIP

Announcements;Facts (“vocabulary”);In vivo DNA binding pattern of the b Txn Factor ;1;1A;;?-2’-deoxyribose;Sugar “Pucker” Conformations;Pyrimidines;G (Keto) G (Enol) A;Base Adenine Guanine Thymine Cytosine;A very useful number:660;Rotation About the N-Glycosidic Bond;Phosphodiester Backbone;;;;11;Note to self:Discuss forces that affect helix formation ;C-G;A;;A;A;;Question: is all B-DNA structurally identical?;Degrees of freedom: 7 Torsion angles and sugar conformation;Structural Variation Defined by Bases;;;19;Pyrimidine-Pur