Agilent Implementation of the Pressure Controlled Tee for Backflushing for the 7000 Series Triple Quadrupole Mass Spectrometer Implications for Sensitivity说明书用户手册.PDF

Implementation of the Pressure Controlled Tee for Backflushing for the 7000 Series Triple Quadrupole Mass Spectrometer: Implications for Sensitivity Application Note Environmental, Drug testing, Forensics and Metabolomics Author Abstract Harry Prest The 7000 Series Triple Quadrupole Mass Spectrometer is designed to provide the Agilent Technologies, Inc. most sensitive and specific analytical determinations in gas chromatography. The Santa Clara, CA enhanced specificity of GC/MS/MS analysis encourages a more relaxed or minimized USA sample preparation strategy with the aim of higher sample throughput and sample turnaround time. However these more complex samples can rapidly degrade the gas chromatograph (GC) and mass spectrometer (MS) performance. Applying backflush- ing helps maintain the GC and the MS source by removing later eluting compounds from the column before reaching the MS, and prior to the next sample injection. This note cites the results of the Pressure Controlled Tee (PCT) configuration for rapid and universal GC/MS backflushing applied to selected reaction monitoring experiments on the Agilent 7890 GC used with the Agilent 7000 Series Triple Quadrupole Mass