光动力靶向放疗MTRT与分子影像诊断ppt课件.pptxVIP

光动力靶向放疗（MTRT)与 分子影像诊断;;第一部分;;;;;第二部分; MTRT和分子影像的设备配置 ;MTRT和分子影像的设备配置;;MTRT和分子影像的设备配置;第三部分;临床应用;;;临床应用;临床应用;临床应用;临床应用;临床应用;临床应用;临床应用;临床应用;临床应用;;;;;;高能X线（45MV），有明显原卟啉IX的激活作用;;MTRT的治疗原理;;2、具有光动力治疗癌症的基本作用：45MV的X光进入体内后，在组织间产生光（契伦科夫效应 ）；虽然光是微弱的，但是增加辅酶和45MV的X线光核反应的电四极作用，起到了正常光动力中光的作用，光、光敏剂和氧产生单态氧，损伤线粒体膜，造成癌细胞死亡或者凋亡。解决了DNA受伤端位修复的治疗难题； ;核反应堆中的契伦科夫辐射、高能宇宙γ射线级联正负电子契伦科夫辐射示意图;3、45MV的X线激发体内水产生双氧水，光、光敏剂和双氧水产生单态氧，无论在癌细胞乏氧和不乏氧的状态下，损伤线粒体膜，造成癌细胞死亡或者凋亡。解决了乏氧癌细胞不敏感的癌症治疗难题。 ; 乏氧状态下有效;4、服药后4小时，每次局部适型治疗，X线放射量在5-8GY，即使药物浓度降低100倍，也可以得到足够的氧自由基，由此解决了肿瘤病灶中缺血，药物浓度低的问题。;;临床应用;临床应用;;; 治疗前;;;XG效果;;3; One week after therapy;;第四部分;;;合规性： 药物喜泊分SFDA批准治疗肿瘤; 也可以使用食品级发酵谷氨酸生成的酮戊酸; LA45 PET-MR设备合规。 ;58;此课件下载可自行编辑修改，供参考！ 感谢您的支持，我们努力做得更好！;月度/季度/年度计划总结汇报PPT模板;;61;62;Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industrys standard dummy text ever since the 1500s, when an unknown printer took a galley of type and scrambled it to make a type specimen book. It has survived not only unchanged. It was popularised in the 1960s with the release of survived printing and typesetting industry. standard dummy text ever since scrambled it to make a type specimen book. It has survived not only five centuries, but;64;请输入标题;请输入标题;;68;69;70;71;72;73;请输入标题请输入标题 ;Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industrys standard dummy text ever since the 1500s, when an unknown printer took a galley of type and scrambled it to make a type specimen book. It has survived not not only five centuries, but also the leap into electronic typesetting.;;77;78;79;;请输入标题请输入标题 ;;谢谢观看