交感神经系统与受体阻断剂.pptVIP

Schlaich MP Circulation 2003;108:560 高血压交感活性增加的危害 去甲肾上腺素释放增加 交感活性与左室重量 A 70 60 50 40 30 20 10 0 HEART Cardiac NE spillover (ng/min) NT EH- EH+ 100 80 60 40 20 0 MSNA (burals/105 heartbeaths) MSNA NT EH- EH+ 250 200 150 100 50 0 B C KIDNEY NT EH- EH+ Renal NE spillover (ng/min) 200 A 160 140 120 100 80 60 40 20 0 Left Vontilcular Miss inder (g/m2) 200 C 160 140 120 100 80 60 40 20 0 Left Vontilcular Miss inder (g/m2) 200 D 160 140 120 100 80 60 40 20 0 Left Vontilcular Miss inder (g/m2) 180 180 180 0 10 20 30 40 50 60 70 Cardiac NE Spillover (ng/min) 0 200 400 600 800 1000 1200 1400 Whole Body