适形放疗联合NP化疗与单纯NP化疗治疗晚期非小细胞肺癌临床疗效分（临床医学范文）.docVIP

适形放疗联合NP化疗与单纯NP化疗治疗晚期非小细胞肺癌临床疗效分（临床医学范文） 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：适形放疗联合NP化疗与单纯NP化疗治疗晚期非小细胞肺癌临床疗效分 2 1 资料与方法 4 1.1 临床资料 4 1.2 治疗方法 4 文2：适形放疗联合NP化疗与单纯NP化疗治疗晚期非小细胞肺癌临床疗效分析 5 1 资料与方法 7 1.1 临床资料 7 1.2 治疗方法 7 1.3 疗效及毒副反应判断标准 8 1.4 统计方法 8 2 结 果 9 2.1 近期疗效 9 2.2 治疗后疾病进展时间与生存、生活质量变化情况 9 2.3 毒副反应 9 3 讨 论 10 参考文摘引言： 11 原创性声明（模板） 13 文章致谢（模板） 13 正文 适形放疗联合NP化疗与单纯NP化疗治疗晚期非小细胞肺癌临床疗效分（临床医学范文） 文1：适形放疗联合NP化疗与单纯NP化疗治疗晚期非小细胞肺癌临床疗效分 ABSTRACT：Objective To analyze retrospectively the clinical effects and side effects of conformal radiotherapy combined with NP chemotherapy and NP chemotherapy for advanced nonsmall cell lung cancer. Methods 76 patients with Ⅲ and Ⅳ stage nonsmall cell lung cancer were grouped. Chemotherapy group coisted of 31 patients, treated with NP chemotherapy. The NP regimen includes Navelbine (25mg/m2, d1, d8) and DDP (25mg/m2, d13), repeated every 21 days. Radio chemotherapy group coisted of 45 patients, receiving threedimeional conformal radiotherapy(3DCRT) combined with NP chemotherapy. Conventional fraction 3dimentional conformal radiotherapy was performed, using 15MV xrays from linear accelerator, after 2 cycles of NP chemotherapy, with total dose 36 to 66 Gy. Then, two more cycles of NP chemotherapy were performed. Prophylactic supraclavicular irradiation was delivered, using 8MeV Electron Beam with total dose of 20 to 30Gy. Results The overall respoe rate(RR) was 57.8% in the radiochemotherapy group, with 3 patients achieved complete respoes, 32.3% in the chemotherapy group, there was a significent difference(P＜0.05) between RR of the two groups. In the radiochemotherapy group, RR was 65.6% in patients with squamous cell carcinoma, 41.7% in patients with adenocarcinoma,there was a statistical difference(P＜0.05) between RR of the two types. RR of the stage ⅢA, ⅢB and Ⅳ was 83.3%, 61.1% and 33.3% respectively, there were statistical differences(P＜0.05) among RR of the three stages. RR