Biotinyl-NH-PEG3-C3-amido-C3-COOH-DIPEA-DataSheet-生命科学试剂-MedChemExpress.pdf

Hotline: 400-820-3792 Inhibitors • Screening Libraries • Proteins www.MedChemE Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA) Cat. No.: HY-130142 CAS No.: 1205744-09-7 分⼦式: C₃₃H₆₃N₅O₈S 分⼦量: 689.95 作⽤靶点: PROTAC Linkers 作⽤通路: PROTAC 储存⽅式: Please store the product under the recommended conditions in the Certificate of Analysis. BIOLOGICAL ACTIVITY ⽣物活性 Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA) 是⼀种 PROTAC linker，属于 PEG 类。可⽤于合成 PROTAC 分⼦。 体外研究 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. REFERENCES [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. McePdfHeight Caution: Product has not been fully validated for medical applications. For research use only. Tel: 400-820-3792; 021 Fax: 021 E-mail: tech@