肾功能衰竭课件.pptVIP

1Renal Failure 2Section I . Introduction 3 But also regulate a variety of material in plasma to maintain the homeostasis of internal environment (osmolality and acid-base balance) Kidneys are the principal excretive organsNot only excrete waste metabolic products to remove various harmful substances, Besides, kidneys also produce some bioactive substances renin, prostaglandins (regulation of blood pressure) erythropoietin (formation of matured RBCs) active vitamin D (metabolism of calcium and phosphorus) 4 But also regulate a variety of material in plasma to maintain the homeostasis of internal environment (osmolality and acid-base balance) Kidneys are the principal excretive organsNot only excrete waste metabolic products to remove various harmful substances, Besides, kidneys also produce some bioactive substances renin, prostaglandins (regulation of blood pressure) erythropoietin (formation of matured RBCs) active vitamin D (metabolism of calcium and phosphorus) 5The following pathologic process is termed renal failure:Glomerular filteration rate↓ Retention of metabolic wastes, Disturbanc of internal environment UremiaRenal Failure Acute renal failure (ARF) (CRF) Cronic renal failurea serial of clinical manifestationsVarious causesSeverely impair renal function 6 1. Causes of renal dysfunction (1) Primary renal disease (2) Renal injury secondary to systemic diseases. 7 1. Causes of renal dysfunction (1) Primary renal disease (2) Renal injury secondary to systemic diseases. 1) Glomerular disease 2)?Renal tubular disease 3) Interstitial nephritis 4) Others:glomerulonephritis; nephrotic syndrome renal glucosuria; aminoaciduria, renal tubular acidosisacute or chronic interstitial inflammationrenal injury, tumor, calculus; obstructive nephropathy; vascular nephropathy 8 1