生物信息学进展教学：jw-生物信息学进展.pptxVIP

生物信息学进展姜伟外语学馆411室MicroRNA Systems Biology Targeting MicroRNAs With Small Molecules: From Dream to Reality第一页，共四十五页。 生物信息学进展姜伟MicroRNA Systems Biology第二页，共四十五页。 IntroductionCentral dogma of molecular biologyChallenged by tiny fragments of noncoding RNAmiRNA, ~22 nucleotides, negatively regulate protein-coding genes, central posttranscriptional regulators of gene expressionVia imperfect base pairing to the 3’UTR of target mRNAs: repression of protein production or mRNA degradation第三页，共四十五页。 IntroductionHave been found in diverse plants, animals, some viruses and even algae (藻类) speciesAll mul