Oleana-2-12-dien-28-oic-acid-DataSheet-生命科学试剂-MCE.pdf

Hotline: 400-820-3792 Inhibitors • Screening Libraries • Proteins www.MedChemE Oleana-2,12-dien-28-oic acid Cat. No.: HY-148201 CAS No.: 272108-04-0 分⼦式: C₃₀H₄₆O₂ 分⼦量: 438.69 作⽤靶点: HBV 作⽤通路: Anti-infection 储存⽅式: Please store the product under the recommended conditions in the Certificate of Analysis. BIOLOGICAL ACTIVITY ⽣物活性 Oleana-2,12-dien-28-oic acid 是⼀种 HBV-DNA 抑制剂，HBsAg 和 HBeAg 抑制剂。oleana -2,12-dien-28-oic acid 可⽤于⼄型肝炎病毒感染的疾病的研究。 体外研究 Oleana-2,12-dien-28-oic acid (4-100 μg/mL; 7 d) shows the inhibition on hepatitis B surface antigen (HBsAg) and hepatitis B e antigen (HBeAg) secreted by HepG2.2.15 cells [1]. Oleana-2,12-dien-28-oic acid (4-100 μg/mL; 7 d) inhibits the replication of hepatitis B virus deoxyribonucleic acid (HBV-DNA) of HepG2.2.15 cells [1]. Cell Viability Assay [1] Cell Line: HepG2 .2 .15 cells Concentration: 4, 20, 100 μg/mL Incubation Time: 7 days Result: Inhibited hepatitis B surface antigen (HBsAg) of 60.5%, 69.8%, and 85.3% at 4, 20, and 100 μg/mL, respectively. Inhibited hepatitis B e antigen (HBeAg) of 45.1%, 60.5%, and 76.9% at 4, 20, and 100 μ