分子生物学DNA复制.pptxVIP

分子生物学DNA复制;The importance of DNA replication to medicine;Replicon;DNA structure: review;Three basic rules of DNA replication;Most of what we will be discussing at first is DNA replication in E. coli Once we have the general principles, we will discuss DNA replication in eukaryotes;How complex is the DNA replication machinery?;第8页/共104页;Semi-conservative (Messelson Stahl, 1958) ;During replication each of the old strands will serve as a template for the new strands;DNA Polymerases;Bidirectional ;When a replicon is circular, the presence of DNA replication forms the θ-structure. The su