肾素血管紧张素系统抑制药.pptVIP

第22章 肾素－血管紧张素系统抑制药 Renin-Angiotensin System Inhibitors 江西医科大学 何 明 第一页，共十九页。 The renin-angiotensin system, an important endocrine system, participates significantly in the pathophysiology of several highly prevalent diseases, which has led to an enormous effort to explore all aspects of the renin-angiotensin system and to devise new approaches for inhibiting its actions. 肾素－血管紧张素系统Rennin-Angiotensin System 第二页，共十九页。 angiotensinogen renin PD123319 angiotrnsin Ⅱ angiotrnsin Ⅰ inactive peptides vasoconstriction sympathetic stimulation cellular hypertrophy renovascular ef