免疫抑制剂在风湿病的应用.pptVIP

Immunosuppressive drugsdampen the immune system—notably T and B lymphocytes—functionally and/or numerically but do not permanently correct the fundamental imbalance of immune regulation in autoimmune disease.第二页，共四十页。 免疫抑制剂的共性Effective and indispensable as remission-inducing and maintenance agents in the management of inflammatory rheumatic conditions. Constitute a heterogeneous group of compounds, each with a unique mode of action and toxicity profile. Associated with an increased risk of bacterial, viral, and fungal infection第三页，共四十页。 脱氧核苷酸核苷酸嘌呤合成嘧啶合成细胞因子、酶等微管6-硫嘌呤6-硫鸟嘌呤抑制嘌呤合成甲氨蝶呤抑制嘌呤合成抑制dTM