生物信息在临床遗传的运用.pptxVIP

第1页/共91页生物信息在临床遗传的运用第2页/共91页概要如何绘制家系图？如何获得疾病的遗传信息？如何读测序结果？如何确定序列改变性质？如何确定突变与疾病的关系?第3页/共91页一、如何绘制家系图？//第4页/共91页Cyrillic 2 特征：View up to 9 families in different Windows Cut and paste families or parts of families Toolbar icons, status bar and tooltips guide new users Switch between tree and circular display Maximum of 10,000 individuals per family and 250 markers per chromosome Tools for speed-drawing of new families Space drawings evenly第5页/共91页Cyrillic 2 特征（续）：Color haplotype bars to show inheritance and multiple crossovers Crossovers calculated from phenotype data Many new input and out