组织学与胚胎学血液双语教学.pptxVIP

组织学与胚胎学血液双语教学;Learning Objectives ;* a specialized form of C.T. * a circulating tissue * as a transporting medium * a total volume about 5 liters in health adult;Components of blood 血液的组成成分 ;血液的组成;血块、血清;血液有形成分;Wright染色法（瑞特染色法）:染料是由酸性染料伊红和碱性染料亚甲蓝组成。 与酸性染料伊红结合，染粉红色；与碱性染料亚甲蓝结合，染紫蓝色。 Giemsa染色法（吉姆萨染色法）:吉姆萨染液由伊红，天青组成。 ;一、红细胞（erythrocyte,red blood cell, RBC）;;;2．ABO血型抗原系统：红细胞膜含血型抗原 A型：有A型抗原 B型：有B型抗原 O型：无A型、B型抗原 AB型：有A型、B型抗原; * not fully mature RBC * 0.5 ?1% of a total number of RBC * no nucleus * ribosomal RNA remnants (netlike structure) * remaining Hb synthesis * Clinic significance ;;;Normal RBC Sickled RBC 镰状;;Typically, the affected RBCs are small, spherically shaped, and lack the light centers seen in normal RBCs. ;General characteristic of leukocytes * spherical shape * posses nuclei * presence of organelles * a total number less than that of erythrocytes * exhibiting amoeboid movement * involving in body defenses and immunity; ;;;中性粒细胞模式图（示杆状核演变至5叶核, 新生到衰老）;中性粒细胞 （血涂片）;Specific granules (80%, samll) contain: alkaline phosphatase 碱性磷酸酶 * Phagocytin 吞噬素 * lysozyme 溶菌酶;Function;; Basophil ;;（电镜）;Function;Neutrophils: * ruffled membrane movement * chemetaxis * phagocytosis Eosinophils: anti-parasite; anti-allergy Basophils: * anticoagulation; * involving in allergic response ;Size: 14 ?20 μm (diameter) Nucleus: large, eccentric, light staining, deep indentation, horseshoe cytoplasm： abundant，gray-blue staining, weak basophilia, numerous purple granules (azurophilic G) ;第34页/共56页;;Function of monocyte ;Lymphocytes 淋巴细胞;* a large number of free ribosomes, * a few mitochondria, and other organelles * exhibiting small cytoplasmic projections in the surface of cells. ; Classification* function# T-Cell: 75% cellular immunity B-Cell: 10-15% humoral immunity