消化性溃疡疾病遗传药理学.pptVIP

Frequencies of CYP2C19 genotypes in patients with eradication and non-eradication of H. pylori infection by triple opz or lpz /amoxicillin /clarithromycin therapy. 胃溃疡治愈与治疗失败病人中CYP2C19不同基因型频率（三联用药） 第三十页，共五十七页，2022年，8月28日 CYP2C19不同基因型对不同剂量PPI抑制胃酸分泌的影响 Median nocturnal intragastric pH values with different dosing regimens of rabeprazole in 3 CYP2C19 genotype groups. In homozygous EMs the median nocturnal pH attained by 10 mg 4 times daily was highest. The median nocturnal pH values attained by divided-dose regimens in heterozygous EMs and with 20 mg once daily in PMs were sufficiently elevated.