胰岛素抵抗的病理生理机制和治疗选择详解演示文稿.pptVIP

In JAMA in 2001, a paper was published that asked the question, What was the impact of ramipril on progression to type 2 diabetes in individuals who did not have diabetes at baseline? There was a very significant reduction in the progression to self-reported diabetes in the HOPE trial in the group taking ramipril vs placebo. I need to emphasize a couple things. This is self-reported diabetes, so they did not have repeated fasting blood glucoses in this study to be able to formally diagnose diabetes. Its self-reported, so we have to be careful, as that has limitations. But nevertheless, this su