药理学英文版教学课件：Chapter 8 Adrenoceptor Antagonist.pptVIP

1 Adrenoceptor Antagonists(P66) Case 1A patient with pheochromocytoma(嗜铬细胞瘤) had a BP of 250/150 mmHg and was i.v. injected phentolamine rapidly, resulted in BP decreasing to 65/40 mmHg.Why this happened, how to deal with the condition? 3 receptors and prevent their activation by catecholamines and related agonists.Classification: α-R antagonists β-R antagonists α,β antagonists. Their major effect is to occupy eitherα, or β 4 Beta-receptor antagonist drugs are firmly established in the treatment of hypertension, ischemic heart disease, arrhythmias, endocrinologic and neurologic disorders, and