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SPINE Volume 29, Number 17, pp 1938 –1944
©2004, Lipp ott Williams Wilkins, .
Adjacent Segment Disease after Lumbar or
Lumbosacral Fusion: Review of the Li ture
Paul Park, MD, Hugh J. Garton, MD, MHsc, Vishal C. Gala, MD, Julian T. Hoff, MD,
and John E. McGillicuddy, MD
Study Design. Review of the li ture. when indicated, consists of pression of neural ele-
Objectives. Review the definition, etiology, idence, ments and extension of fusion. es after surgery,
and risk factors associated with as well as potential treat- however, are modest.
ment options. : adjacent segment disease, review, spinal
Summary of Background Data. The development of fusion, transition syndrome. Spine 2004;29:1938 –1944
pathology at the segment next to a lumbar or
lumbosacral spinal fusion has been termed adjacent seg- No funds were received in support of this work. No benefits in any form
ment disease. Initially reported to occur rarely, it is now have been or will be received from a commercial party related directly
considered a potential late complication of spinal fusion or indirectly to the subject of this manuscript.
that can necessitate further surgical intervention and ad- Address reprint requests
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