《病理生理学》课件肺功能障碍.pptVIP

? ? ? ? COPD Hypoventilation Ventilation-perfusion imbalance Diffusion impairment Hypoventilation Obstructive Restrictive Congestion,swelling, spasm, blockage of bronchi wall Decreased alveolar surfactant Respiratory muscle failure Decreased alveolar surface area Low ventilation in part of alveoli Low blood flow in part of alveoli Chronic obstructive pulmonary disease (COPD) is chronic airway obstruction caused by chronic bronchitis and emphysema. 慢性阻塞性肺疾病（COPD）→呼吸衰竭 本文档共44页；当前第30页；编辑于星期五\21点53分 呼吸衰竭时主要代谢功能变化 外呼吸功能严重障碍→PaO2↓或伴PaCO2↑→低氧血症、高碳酸血症及酸碱平衡紊乱→机能代谢变化的根本原因