p-Iodoclonidine-hydrochloride-DataSheet-生命科学试剂-MCE.pdf

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p-Iodoclonidinehydrochloride

Cat.No.:HY-112658

CASNo.:108294-57-1

分⼦式:C₉H₉Cl₃IN₃

分⼦量:392.45

作⽤靶点:AdrenergicReceptor;AdenosineReceptor

作⽤通路:GPCR/GProtein;NeuronalSignaling

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性p-Iodoclonidinehydrochloride是α2-肾上腺素受体的部分激动剂。p-Iodoclonidinehydrochloride在抑制⾎

⼩板膜中的腺苷酸环化酶⽅⾯也具有⼀定程度的激动剂活性，并增强ADP诱导的⾎⼩板聚集，EC50为1.5μ

M。

REFERENCES

[1].GerhardtMA,etal.p-[125I]iodoclonidineisapartialagonistatthealpha2-adrenergicreceptor.MolPharmacol.1990Aug;38(2):214-21.

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