超声引导局部注射甲氨喋呤治疗未破裂型宫外孕临床疗效观察.docxVIP

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超声引导局部注射甲氨喋呤治疗未破裂型宫外孕临床疗效观察

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【摘要】目的：对经超声引导局部注射甲氨喋呤治疗未破裂型宫外孕的效果和可行性进行分析。方法：将我院自2014年6月到2017年3月间收治的94例未破裂型宫外孕患者按照治疗方式随机分为两组，对照组采用甲氨蝶呤肌注的方式进行治疗，实验组则使用超声引导的局部注射甲氨蝶呤的方式进行治疗。对比两组患者治疗效果的差异。结果：超声引导下局部注射甲氨蝶呤对于患者治疗的效果显著优于肌肉注射。实验组患者注射甲氨蝶呤后一周，患者的血β-HCG水平下降率及异位妊娠包块体积缩小程度均显著优于对照组。对照组肌注引起患者不良发应发生的概率显著高于实验组。差异均有统计学意义(P＜0.05)。结论：超声引导下局部注射甲氨蝶呤对于未破裂型宫外孕患者治疗的效果显著，且治疗引起的不良反应小，安全性高，具有临床应用的价值。

【关键词】超声引导；甲氨蝶呤；未破裂型宫外孕；临床效果

R714.22A2095-1752（2018）01-0046-02

UltrasoundobservationoflocalinjectionofmethotrexatetreatmentofunrupturedectopicpregnancycurativeeffectTangYaoqiong.

YanyuanCountyMaternalandchildhealthfamilyplanningservicecenterofObstetricsandGynecology,SichuanLiangshan615700

【Abstract】ObjectiveUltrasoundguidedlocalinjectionofmethotrexatetreatmentofunrupturedectopicpregnancyeffectandfeasibilitywereanalyzed.MethodsInourhospitalfromJune2014toMarch2017were94casesofunrupturedectopicpregnancypatientsaccordingtotreatmentwererandomlypidedintotwogroups,thecontrolgroupwastreatedwithmethotrexateintramuscularinjectionwaythetreatment,theexperimentalgroupusingtheultrasound-guidedlocalinjectionofmethotrexateforthetreatmentoftheway.Thedifferenceswerecomparedbetweentwogroups.ResultsThetherapeuticeffectofultrasonictreatmentforpatientsissignificantlybetterthanintramuscularinjectionoflocalinjectionofmethotrexateundertheguidance.Oneweekaftertheinjectionofmethotrexateinpatientsintheexperimentalgroup,serum-HCGlevelsinpatientswiththedeclinerateandectopicpregnancymassvolumedecreasedsignificantlythanthecontrolgroup.Thecontrolgroupwerecausedbyadverseresponseprobabilityofoccurrencewassignificantlyhigherthanthatintheexperimentalgroup.thedifferencewasstatisticallysignificant(P0.05).ConclusionUltrasoundguidedlocalinjectionofmethotrexateforectopicpregnancyinpatientswithsignificantcurativeeffect,andthetreatmentofadversereactionscausedbysmall,highsafety,clinicalapplicationhasapriceValue.

【Keywords】Ultrasoundguided;Methotrexate;Unrupturedectopicpregnancy;Clinicaleffect

随着人们生活、饮食习惯的变化及生活环境的不断变化，异位妊娠在女性中的发生率也呈现出