盐酸米诺环素联合布洛芬对慢性牙周炎的疗效观察.pdfVIP

盐酸米诺环素联合布洛芬对慢性牙周炎的疗效观察

摘要目的探讨盐酸米诺环素联合布洛芬对慢性牙周炎的临床疗效。方法

120例慢性牙周炎患者，随机分成观察组和对照组，每组60例。两组患者均

予以超声洁刮治疗，对照组使用盐酸米诺环素治疗，观察组使用盐酸米诺环素

联合布洛芬治疗，比较两组患者治疗效果以及治疗前后的菌斑指数、菌落数量、

龈沟出血指数。结果治疗后，两组患者的菌斑指数、菌落数量、龈沟出血指数

均明显低于治疗前，观察组患者的菌斑指数、菌落数量、龈沟出血指数明显低

于对照组，差异具有统计学意义（P＜0.05）。观察组患者的治疗总有效率为

98.3%，显著高于对照组的85.0%，差异具有统计学意义（P＜0.05）。

结论盐酸米诺环素联合布洛芬对慢性牙周炎的疗效明显，值得推广应用。

关键词盐酸米诺环素；布洛芬；慢性牙周炎；临床疗效

Observationoftheefficacyofminocyclinehydrochlorideandibuprofeninthe

treatmentofchronicperiodontitisZHAOXue-kui.DepartmentofStomatology，

ShandongTanchengFirstPeople’sHospital，Linyi276199，China

【Abstract】ObjectiveTodiscusstheclinicalefficacyofminocycline

hydrochlorideandibuprofeninthetreatmentofchronicperiodontitis.MethodsAtotal

of120chronicperiodontitispatientswererandomlydividedintoobservationgroup

andcontrolgroup，with60casesineachgroup.Bothgroupsreceivedultrasonic

curettagetherapy，andthecontrolgroupreceivedminocyclinehydrochloridefor

treatment.Theobservationgroupreceivedminocyclinehydrochlorideandibuprofen

fortreatment.Comparisonweremadeontreatmenteffect，plaqueindex，colony

number，gingivalbleedingindexbeforeandaftertreatmentbetweentwogroups.

ResultsAftertreatment，bothgroupshadobviouslylowerplaqueindex，colony

number，gingivalbleedingindexthanbeforetreatment，andtheobservationgroup

hadobviouslylowerplaqueindex，colonynumber，gingivalbleedingindexthanthe

controlgroup.Theirdifferencewasstatisticallysignificant（P＜0.05）.The

observationgrouphadobviouslyhighertotaltreatmenteffectiverateas98.3%than

85.0%inthecontrolgroup，andthedifferencewasstatisticallysignificant（P＜

0.05）.ConclusionCombinationofminocyclinehydrochlorideandibuprofenprovides

remarkableefficacyforchronicperiodontitis，andiswort