黄芪当归补血汤预防老年骨折患者术后非感染性发热的疗效分析 (1).docx

黄芪当归补血汤预防老年骨折患者术后非感染性发热的疗效分析

【摘要】目的：观察分析黄芪当归补血汤预防老年骨折患者术后非感染性发热的综合疗效。方法：选取2020.05~2022.05本院收治的110例老年骨折术后非感染性发热患者分为对照组、观察组，各55例。对照组常规治疗，观察组增加黄芪当归补血汤治疗。综合评估两组患者的临床疗效、中医症候积分、血常规指标、炎症因子水平、治疗安全性等指标。结果：观察组总有效率为92.73%(51/55)，高于对照组为76.36%(42/55)(P0.05)。治疗后观察组中医症候积分肌热面红、头昏眼花、烦渴欲饮、面白少华等均低于对照组(P0.05)。治疗后观察组血常规指标包括红细胞计数(RBC)、血红蛋白(Hb)、红细胞比容(HCT)水平均高于对照组(P0.05)。治疗后观察组炎症因子Toll样受体4(TLR4)、核因子κB(NF-κB)、前列腺素E2(PGE2)水平均低于对照组(P0.05)。治疗期间观察组、对照组不良反应发生率为12.73%(7/55)、9.09%(5/55)(P0.05)。结论：黄芪当归补血汤预防老年骨折患者术后非感染性发热的疗效显著，可改善中医症候、血常规指标，抑制各种炎症因子的表达，治疗安全性良好。

【关键词】老年骨折患者；非感染性发热；黄芪当归补血汤；临床疗效；中医症候

EffectofHuangqiDangguiBuxueDecoctiononpreventingpostoperativenoninfectiousfeverinelderlypatientswithfracture

[Abstract]Objective:ToobserveandanalyzethecomprehensiveeffectofHuangqiDangguiBuxueDecoctiononpreventingpostoperativenoninfectiousfeverinelderlyfracturepatients.Methods:110elderlypatientswithnoninfectiousfeverafterfracturesurgerytreatedinourhospitalfromMay2020tomay2022wereselectedassubjects.Theywererandomlydividedintocontrolgroupandobservationgroupbycomputerlottery,with55cases.Thecontrolgroupwastreatedwithconventionalwesternmedicine,andtheobservationgroupwastreatedwithAstragalusandAngelicaBuxueDecoction.Theclinicalefficacy,TCMsymptomscore,bloodroutineindex,inflammatoryfactorlevelandtreatmentsafetyofthetwogroupswerecomprehensivelyevaluated.Results:theobservationgrouptotaleffectiveratewas92.73%(51/55),higherthancontrolgroup76.36%(42/55)(p0.05).Aftertreatment,theobservationgroupscoreofTCMsymptomslowerthancontrolgroup(p0.05).Aftertreatment,theobservationgroupbloodroutineindexesincludingRBC,HbandHCTwerehigherthanthoseinthecontrolgroup(p0.05).Aftertreatment,theinflammatoryfactortolllikereceptor4(TLR4)andnuclearfactorintheobservationgroupκB(NF-κB)AndprostaglandinE2(PGE2)levelswerelowerthanthoseintheco