Corticotropin-releasing-hormone-CRH-生命科学试剂-MCE.pdf

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Corticotropin-releasinghormone

Cat.No.:HY-P3538

CASNo.:9015-71-8

Synonyms:CRH

分⼦式:C₂₀₅H₃₃₉N₅₉O₆₃S

分⼦量:4667.49

Sequence:Ser-Gln-Glu-Pro-Pro-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Le

u-Arg-Glu-Val-Leu-Glu-Met-Thr-Lys-Ala-Asp-Gln-Leu-Ala-Gln-

Gln-Ala-His-Ser-Asn-Arg-Lys-Leu-Leu-Asp-Ile-Ala-NH2

SequenceShortening:SQEPPISLDLTFHLLREVLEMTKADQLAQQAHSNRKLLDIA-

NH2

作⽤靶点:Others

作⽤通路:Others

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Corticotropin-releasinghormone(CRH)是⼀种参与应激反应的肽激素。Corticotropin-releasinghormone

(CRH)是应激条件下下丘脑-垂体-肾上腺(HPA)轴的主要调节肽。Corticotropin-releasinghormone(CRH)可

⽤于神经内分泌和焦虑样⾏为的研究。

REFERENCES

[1].RZhang,etal.Lossofhypothalamiccorticotropin-releasinghormonemarkedlyreducesanxietybehaviorsinmice.MolPsychiatry.2017

May;22(5):733-744.

[2].KazunoriKageyama,etal.Signaltransductioninthehypothalamiccorticotropin-releasingfactorsystemanditsclinicalimplicat