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HYNIC-UBI29-41
Cat.No.:HY-P10913
CASNo.:1186217-15-1
分⼦式:C₇₄H₁₂₆N₃₄O₁₉S
分⼦量:1828.07
Sequence:{HYNIC-Thr}-Gly-Arg-Ala-Lys-Arg-Arg-Met-Gln-Tyr-Asn-Arg-Ar
g
SequenceShortening:{HYNIC-Thr}-GRAKRRMQYNRR
作⽤靶点:Bacterial
作⽤通路:Anti-infection
储存⽅式:Pleasestoretheproductundertherecommendedconditionsin
theCertificateofAnalysis.
BIOLOGICALACTIVITY
⽣物活性HYNIC-UBI29-41由双功能螯合剂HYNIC和抗菌肽UBI29-41组成。HYNIC-UBI29-41保留了UBI29-41的抗菌
特性,对⾰兰⽒阳性菌和⾰兰⽒阴性菌均表现出良好的亲和⼒。HYNIC-UBI29-41⽤放射性元素Technetium
(99mTc)标记后,可在⼩⿏模型中作为细菌感染检测的成像剂[1]。
REFERENCES
[1].WellingMM,etal.,Infectiondetectioninmiceusing99mTc-labeledHYNICandN2S2chelateconjugatedtotheantimicrobialpeptide
UBI29-41.NuclMedBiol.2004May;31(4):503-9.
McePdfHeight
Caution:Producthasnotbeenfullyvalidatedformedicalapplications.
Forresearchuseonly.
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