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BAR-072

Cat.No.:HY-168995

CASNo.:2068867-65-0

分⼦式:C₁₈H₁₃N₃O₆

分⼦量:367.31

作⽤靶点:Bacterial

作⽤通路:Anti-infection

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性BAR-072是⼀种靶向TraE的⼩分⼦抑制剂，KD为2.7µM。BAR-072能显著抑制抗⽣素耐药性相关质粒

pKM101的转移。BAR-072有望作为⽤于抑制细菌耐药基因传播的候选分⼦，⽤于抗感染和耐药性控制等疾病

领域的研究[1]。

REFERENCES

[1].CasuB,etal.StructuralAnalysisandInhibitionofTraEfromthepKM101TypeIVSecretionSystem.JBiolChem.2016Nov

4;291(45):23817-23829.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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1/1MasterofBioactiveMolecules—您⾝边的抑制剂⼤师