基于数据挖掘探析叶天士治内风用药特点.docx

基于数据挖掘探析叶天士治内风用药特点

[摘要]目的探析叶天士治内风的用药特点。方法检索《临证指南医案》中风篇、肝风篇、眩晕篇、头风篇、虚劳篇、肝火篇、不寐篇、痉厥篇、癫痫篇、头痛篇医案，统计医案中证候要素、证候要素靶位、中药频次、性味、归经，分析关联规则和高频药物聚类。结果本研究纳入167篇医案，提取证候要素241个、证候要素靶位333个；纳入183首处方，涉及132味药物，药物总频次1309次。高频中药前5位依次是生地黄、茯神、阿胶、茯苓、熟地黄；药性以寒性最多，其次是温、平；药味以甘性最多，其次是苦、温；归经前5位依次是肝、肾、肺、心、脾。药物关联规则分析得到14项，高频药物聚类得到9类。结论叶天士治内风紧扣“阳化内风”，治疗基础原则为滋液熄风、清上实下、疏肝和胃，兼以辛甘化风、清肝泄热、祛风化痰、益气实卫、清热安神等，调和脏腑经络、平息内风。

[关键词]叶天士；《临证指南医案》；数据挖掘；内风；用药规律

[中图分类号]R252[文献标识码]A[DOI]10.3969/j.issn.1673-9701.2025.05.019

YeTianshi’sapproachtothemanagementofinternalwindutilizingdataminingtechniques

BAIYunxian1，YANGEnfa1，WENLingzhi1，HUANGJianping2

1.DepartmentofNeurology，WenzhouHospitalofTraditionalChineseMedicine，ZhejiangUniversityofTraditionalChineseMedicine，Wenzhou325000，Zhejiang，China;2.DepartmentofNeurology，WenzhouCentralHospital，Wenzhou325000，Zhejiang，China

[Abstract]ObjectiveToexamineofYeTianshi’sapproachtomanaginginternalwindthroughherbalremedies.MethodsAcomprehensivesearchwasconductedformedicalcasespertainingtointernalwind，liverwind，dizziness，headwind，deficiencylabor，liverfire，insomnia，convulsions，epilepsy，andheadachewithintheClinicalGuidelinesinMedicalCases.Statisticalanalysisofsymptomelements，targetlocationsofsymptomelements，frequencyofChinesemedicinalsubstances，theirproperties，andmeridianaffiliationswasperformedusingExcel.Prescriptionpatternswerefurtheranalyzedthroughassociationrulesandhigh-frequencydrugclustering.ResultsThestudyincludedatotalof167medicalcases，fromwhich241symptomelementsand333targetlocationswereextracted.Atotalof183prescriptionswereanalyzed，comprising132medicinalsubstanceswithanoverallfrequencyof1309occurrences.ThefivemostfrequentlyusedChinesemedicineswereShengDiHuang，FuShen，EJiao，FuLing，andShuDiHuang.Thepredominantpropertyobservedwascold，followedbywarmandneutral;themostcommonflavorwassweet，succeededbybitterandwarm.Theleadingmeridianaffiliationsidentifiedwereliver，kidney，lung，heart，andspleen.Thedrugassociationruleanalysisrevealed14items，whilehigh-frequencydrugclusteringresultedin9distinctcateg