Thiamine-triphosphoric-acid-ester-Thiamine-triphosphate-生命科学试剂-MCE.pdfVIP

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Thiaminetriphosphoricacidester

Cat.No.:HY-W587827

CASNo.:3475-65-8

Synonyms:Thiaminetriphosphate

分⼦式:C₁₂H₁₉N₄O₁₀P₃S

分⼦量:504.29

作⽤靶点:EndogenousMetabolite

作⽤通路:MetabolicEnzyme/Protease

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Thiaminetriphosphoricacidester(TTP)是⼀种神经活性化合物，是维⽣素硫胺素的三磷酸衍⽣物。Thiamine

triphosphoricacidester存在于微⽣物、动物器官和植物中。⼤肠杆菌中，当氨基酸缺乏时，Thiamine

triphosphoricacidester会瞬时产⽣，⽽在哺乳动物细胞中，Thiaminetriphosphoricacidester以低速持续

产⽣。Thiaminetriphosphoricacidester可由两种不同的酶合成(胞质中的AK1和脑线粒体中的FoF1-ATP

synthase)。Thiaminetriphosphoricacidester在细胞代谢或细胞信号传导中起着基础作⽤[1][2]。

REFERENCES

[1].MakarchikovAF,etal.Thiaminetriphosphateandthiaminetriphosphataseactivities:frombacteriatomammals.CellMolLifeSci.2003

Jul;60(7):1477-88.

[2].BettendorffL,etal.Thiaminetriphosphate:aubiquitousmoleculeinsearchofaphysiologicalrole.MetabBrainDis.2014

Dec;29(4):1069-82.

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