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BerkeleyamideB

Cat.No.:HY-N16408

CASNo.:1019854-22-8

分⼦式:C₂₀H₂₁NO₆

分⼦量:371.38

作⽤靶点:MMP;Caspase

作⽤通路:MetabolicEnzyme/Protease;Apoptosis

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性BerkeleyamideB是⼀种⾦属蛋⽩酶-3(MMP-3)和caspase-1双重抑制剂。BerkeleyamideB有望⽤于癌症和

炎症性疾病(如类风湿性关节炎)的研究。

IC50TargetCaspase-1MMP-3

REFERENCES

[1].StierleAA,etal.Theberkeleyamides,amidesfromtheacidlakefungusPenicillumrubrum.JNatProd.2008May;71(5):856-60.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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