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AGN-190383

Cat.No.:HY-165327

CASNo.:120755-15-9

分⼦式:C₁₉H₃₂O₅

分⼦量:340.45

作⽤靶点:Phospholipase

作⽤通路:MetabolicEnzyme/Protease

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性AGN-190383是⼀种蜂毒磷脂酶A2(beevenomphospholipaseA2)抑制剂。AGN190383抑制激素作⽤和去

极化依赖的钙动员，以及fMLP刺激的胞质游离钙的增加。AGN-190383具有抗炎活性。

IC50TargetPLA2

REFERENCES

[1].DeVriesGW,etal.AGN190383,anovelphospholipaseinhibitorwithtopicalanti-inflammatoryactivity.AgentsActions.1991Sep;34(1-

2):70-2.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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