DRP1-Allosteric-IN-1-生命科学试剂-MCE.pdfVIP

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DRP1Allosteric-IN-1

Cat.No.:HY-176973

CASNo.:1359386-11-0

分⼦式:C₂₁H₂₂N₂O₂

分⼦量:334.41

作⽤靶点:Dynamin

作⽤通路:Cytoskeleton

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性DRP1Allosteric-IN-1(Compound1)是DRP1的变构抑制剂，其对DRP1：MiD49蛋⽩-蛋⽩相互作⽤的IC50

为3.6μM。DRP1Allosteric-IN-1可⽤于研究线粒体分裂失调相关的多种疾病。

REFERENCES

[1].FuruyaT,etal.DiscoveryofPotentAllostericDRP1InhibitorsbyDisruptingProtein-ProteinInteractionwithMiD49.ACSMedChem

Lett.2023Jul24;14(8):1095-1099.

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1/1MasterofBioactiveMolecules—您⾝边的抑制剂⼤师