DRP1-Allosteric-IN-2-生命科学试剂-MCE.pdfVIP

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DRP1Allosteric-IN-2

Cat.No.:HY-176974

CASNo.:3056559-91-9

分⼦式:C₂₁H₂₃N₃O

分⼦量:333.43

作⽤靶点:Dynamin

作⽤通路:Cytoskeleton

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性DRP1Allosteric-IN-2(Compound2a)是DRP1的变构抑制剂，其对DRP1：MiD49蛋⽩-蛋⽩相互作⽤的IC50

为4.3μM。DRP1Allosteric-IN-2可⽤于研究线粒体分裂失调相关的多种疾病。

REFERENCES

[1].StabenLR,etal.SystematicVariationofPyrrolobenzodiazepine(PBD)-DimerPayloadPhysicochemicalPropertiesImpactsEfficacyand

TolerabilityoftheCorrespondingAntibody-DrugConjugates.JMedChem.2020Sep10;63(17):9603-9622.

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1/1MasterofBioactiveMolecules—您⾝边的抑制剂⼤师