微电子技术论文7509633.pdfVIP

IEEETRANSACTIONSONNUCLEARSCIENCE,VOL.63,NO.5,OCTOBER20162487

ANovelMethodforγ-photonsDepth-of-Interaction

DetectioninMonolithicScintillationCrystals

RobertoPani,Member,IEEE,MarcoBettiol,EnricoPreziosi,CristianBorrazzo,RosannaPellegrini,

AntonioJ.González,PabloConde,MariaNerinaCinti,AndreaFabbri,ElisabettaDiCastro,andStanMajewski

Abstract—AchievedspatialresolutionofthePETsystemsisI.INTRODUCTION

oftenlimitedbytheparallaxerrorduetothelackofinforma-

tionabouttheDepthofInteraction(DoI)insidethecrystaloftheNIMPORTANTandgrowingfieldofresearchandclin-

incoming511keVannihilationphotons.Thesmallerthediame-AicalapplicationsisNeuroimaging.Inthiscontexthybrid

terofthePETringandthethickerthescintillatorare,themorePositronEmissionTomographyandMagneticResonance

thiserroraffectsimagingperformance.Inthiswork,aDoIcal-Imaging(PET/MRI)systemsareveryimportantsincethey

culatorsuitableformonolithicscintillationcrystalsandbasedon

allowbothanatomicalandfunctionalimaging.TheMindView

theshapeofthescintillationlightdistributionatthephotodetec-

torsurfacehasbeenproposed.Totesttheestimatorperformance,EuropeanUnionProjectpursuesabrain-optimizedsimultane-

atestPETmodulewitha50×50×20mmmonolithicLYSOousPET/MRIsystemwithhighsensitivityandhighrecon-

crystalcoupledtoa12×12SiPMarrayhasbeenemployed.Instructedspatialresolution(