Remodelin-C6-COOH-生命科学试剂-MCE.pdfVIP

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Remodelin-C6-COOH

Cat.No.:HY-178361

CASNo.:2966791-35-3

分⼦式:C₂₂H₂₆N₄O₂S

分⼦量:410.53

作⽤靶点:TargetProteinLigand-LinkerConjugates

作⽤通路:PROTAC

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Remodelin-C6-COOH是⼀种合成的靶蛋⽩配体-连接⼦偶联物，可⽤于合成NP1192(HY-178360)。NP1192

是⼀种强效的NAT10PROTAC降解剂，具有抗肿瘤活性。

REFERENCES

[1].Ao,K.,etal.TargetedNAT10DegradationbyPROTACNP1192SuppressesHypoxia-AdaptiveGlycolysisandReinvigoratesCD8+

EffectorT-CellFunctionforSynergisticCancerImmunotherapy.ACSCentralScience.2025.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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