Revefenacin-impurity-4-生命科学试剂-MCE.pdfVIP

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Revefenacinimpurity4

Cat.No.:HY-W801784

CASNo.:1289178-27-3

分⼦式:C₂₀H₂₄N₂O₂

分⼦量:324.42

作⽤靶点:mAChR

作⽤通路:GPCR/GProtein;NeuronalSignaling

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Revefenacinimpurity4(Compound9b)是Revefenacin(HY-15851)的中间体。Revefenacinimpurity4可以

与⼈M3毒蕈碱⼄酰胆碱受体抑制结合(Ki=55nM)。

REFERENCES

[1].HughesAD,etal.Discoveryofmuscarinicacetylcholinereceptorantagonistandbeta2adrenoceptoragonist(MABA)dual

pharmacologymolecules.BioorgMedChemLett.2011Mar1;21(5):1354-8.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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