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SI-2hydrochloride(Standard)

Cat.No.:HY-101447AR

CASNo.:1992052-49-9

分⼦式:C₁₅H₁₆ClN₅

分⼦量:301.77

作⽤靶点:EstrogenReceptor/ERR;ReferenceStandards

作⽤通路:VitaminDRelated/NuclearReceptor;Others

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性SI-2(hydrochloride)(Standard)是SI-2(hydrochloride)(HY-101447A)的分析标准品。本产品⽤于研究及分析

应⽤。SI-2(EPH116hydrochloride)是SRC-3的抑制剂，可以诱导乳腺癌细胞死亡。SI-2(EPH116

hydrochloride)具有良好的药代动⼒学特征和改善的毒性，以及可接受的⼝服可⽤性。

IC50TargetIC50：3-20nM(breastcancercelldeath)[1].

REFERENCES

[1].SongX,etal.Developmentofpotentsmall-moleculeinhibitorstodrugtheundruggablesteroidreceptorcoactivator-3.ProcNatlAcad

SciUSA.2016May3;113(18):4970-5.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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