SDH-IN-42-生命科学试剂-MCE.pdfVIP

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SDH-IN-42

Cat.No.:HY-179287

分⼦式:C₂₁H₂₃F₂N₃O₂

分⼦量:387.42

作⽤靶点:Fungal;MitochondrialMetabolism;ReactiveOxygenSpecies

(ROS)

作⽤通路:Anti-infection;MetabolicEnzyme/Protease;

Immunology/Inflammation;NF-κB

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性SDH-IN-42(CompoundD28)是⼀种SDH抑制剂(IC50：5.38μg/mL)和抗真菌(antifungal)剂。SDH-IN-42

通过破坏菌丝形态、增加细胞膜通透性、诱导ROS的产⽣和积累以及损害线粒体(mitochondrialfunction)功

能，对R.solani发挥抗真菌活性。

IC50TargetIC50:5.38μg/mL[1]

REFERENCES

[1].SuS,etal.Novelβ-IononeDerivativesContainingIsoxazoleHydrazideMoiety:Design,Synthesis,AntifungalActivity,andAction

Mechanism.JAgricFoodChem.2025Nov12;73(45):29160-29170.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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