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GIBH-130(Standard)

Cat.No.:HY-101860R

CASNo.:1252608-59-5

分⼦式:C₂₀H₂₀N₆O

分⼦量:360.41

作⽤靶点:ReferenceStandards;InterleukinRelated

作⽤通路:Others;Immunology/Inflammation

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性GIBH-130(Standard)是GIBH-130(HY-101860)的分析标准品。本产品⽤于研究及分析应⽤。GIBH-130是有

效的神经炎症抑制剂。GIBH-130作⽤于活化的⼩胶质细胞，显著抑制IL-1β分泌，IC50为3.4nM。

IC50TargetIC50:3.4nM(IL-1β),46.24μM(NO),40.82μM(TNF-α)[1]

REFERENCES

[1].ZhouW,etal.Microglia-BasedPhenotypicScreeningIdentifiesaNovelInhibitorofNeuroinflammationEffectiveinAlzheimersDisease

Models.ACSChemNeurosci.2016Nov16;7(11):1499-1507.

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