欧洲药典EP11 介绍.pdfVIP

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EUROPEANPHARMACOPOEIA11.0Lactitolmonohydrate01/2017:1771ASSAYPlace1.000

ginaground-glass-stopperedflaskandadd10

mLofwater

Rand20.0

mLof1

Msodiumhydroxide.Closetheflaskandallowtostandfor30

min.Using0.5

mLofphenolphthaleinsolution

Rasindicator,titratewith1

M(S)-LACTICACIDhydrochloricaciduntilthepinkcolourisdischarged.1

mLof1

Msodiumhydroxideisequivalentto90.1

mgofCHO.Acidum(S)-lacticum363(S)-enantiomerTransferanamountofthesubstancetobeexaminedequivalentto2.00

goflacticacidintoaround-bottomedflask,add25

mL

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