上海交通大学医学院级研究生-文献导读相关知识简介.ppt

AnEpigeneticSwitchInvolvingNF-kB,

Lin28,Let-7microRNA,andIL6Links

InflammationtoCellTransformation

Cell139,693–706,November13,2009

Virusesassociatedwithhumancancers

CellderivedmediatorsNameTypeSourceLysosomegranulesEnzymesGranulocytesHistamineVasoactiveamineMastcells,basophils,plateletsIFN-γCytokineT-cells,NKcellsIL-8ChemokinePrimarilymacrophagesLeukotrieneB4EicosanoidLeukocytesNitricoxideSolublegasMacrophages,endothelialcells,someneuronsProstaglandinsEicosanoidMastcellsTNF-αandIL-1CytokinesPrimarilymacrophages

炎性介质的种类作用

表观遗传学（epigenetics）区别于DNA序列改变的基因