非小细胞肺癌的放射治疗.ppt

非小细胞肺癌-放射治疗

LungCancerScreeningFromPresentationat:2011ASCOAnnualMeetingStageIncidenceTreatment5-YrSurvivalI15-20%SurgeryorSBRT60-80%II5-10%Surgery±Chemotherapy40-50%III30-35%Combined-ModalityTr15-40%IV35-40%Chemo±RT5%

SBRTvs.手术SBRT靶区勾画SBRT毒副反应I期NSCLC-放射治疗

SBRT-InoperablestageINSCLCSBRT是无法耐受手术的外周型I期NSCLC的首选治疗JAMA.2010;303:1070-6.PhaseIItrialofSBRTformedicallyinoperablestageI/IINSCLC-RTOG023655patientsT≤5cm,N0,M020Gyin3fractionsover1.5to2weeksResults3-yearprimarytumorcontrolrate:97.6%Disease-freesurvivalat3years:48.3%Overallsurvivalat