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CARDIOLOGY/SPECIAL CONTRIBUTION
2007 Update to the ACC/AHA Guidelines for the Management
of Patients With Unstable Angina and Non–ST-Segment
Elevation Myocardial Infarction: Implications for Emergency
Department Practice
Charles V. Pollack, Jr, MA, MD From the Pennsylvania Hospital, University of Pennsylvania, Philadelphia, PA (Pollack); and the TIMI
Eugene Braunwald, MD Study Group, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA (Braunwald).
The American College of Cardiology and American Heart Association have updated their guidelines for
the management of non–ST-segment-elevation acute coronary syndrome for the first time since 2002. In
the interim, several important studies affecting choices of therapy potentially begun in the emergency
department have been completed, and care patterns have changed and matured significantly. In this
review, we present the new recommendations that are pertinent to emergency medicine practice and
comment on their potential implementation into an evidence-based, multidisciplinary approach to the
evaluation and management of this challenging patient population. [Ann Emerg Med. 2008;51:
591-606.]
0196-0644/$-see front matter
Copyright © 2008 by the American College of Emergency Physicians.
doi:10.1016/j.annemergmed.2007.09.004
INTRODUCTION DEFINITIONS AND WEIGHTING OF EVIDENCE
The American College of Cardiology (ACC) and the Non–ST-segment-elevation acute coronary syndrome
American Heart Association (AHA) have jointly published comprises a clinical syndrome that presents as anginal chest pain
practice guidelines for various aspects of cardiovascular disease or its equivalent (eg, dyspnea, jaw or arm p
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