Jiang and Lin 2012 Anatomical insights into disrupted small-world networks in schizophrenia文章.pdfVIP

NeuroImage 59 (2012) 1085–1093 Contents lists available at SciVerse ScienceDirect NeuroImage journal homepage: www. elsevi er. com/ locate/ ynimg Anatomical insights into disrupted small-world networks in schizophrenia Qifeng Wang a, Tung-Ping Su b, c, Yuan Zhou d, Kun-Hsien Chou e, I-Yun Chen e, Tianzi Jiang a, f,g,⁎, Ching-Po Lin e,⁎⁎ a LIAMA Center for Computational Medicine, National Laboratory of Pattern Recognition, Institute of Automation, the Chinese Academy of Sciences, Beijing, China b Department of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan c Department of Psychiatry, Collage of Medicine, National Yang-Ming University, Taipei, Taiwan d Key Laboratory of Behavioral Science, Institute of Psychology, Chinese Academy of Sciences, Beijing, China e Brain Connectivity Laboratory, Institute of Neuroscience, National Yang-Ming University, Taipei, Taiwan f Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China g The Queensland Brain Institute, The University of Queensland, Brisbane, Australia a r t i c l e i n f o a b s t r a c t Article history: Schizophrenia is characterized by lowered efficiency in distributed information processing, as indicated by Received 17 March 2011 research that identified a disrupted small-world functional network. However, whether the dysconnection Revised 13 September 2011 manifested by the disrupted small-world functional network is reflected in underlying anatomical disru