145 例肝硬化失代偿期低钠血症的回首性分析.pdfVIP

194 Ch in J C lin i H ep ato l, Ap ril 20 10 , Vo l26,No2 145例肝硬化失代偿期低钠血症的回顾性分析 占国清 ,谭华炳 ,朱 　琳 ,李儒贵 ,杜卫星 ,张薇薇 (郧阳医学院附属人民医院肝病研究室 ,湖北 十堰 442000) 　　【摘要 】目的　探讨肝硬化失代偿期患者不同血清钠水平与病情严重度的关系 。方法 　回顾性分析我科收治 145例肝硬化腹水伴低钠血症患者 ,根据其入院时血清钠水平分为低钠血症轻 、中、重度组 , 比较 3 组肝肾功能、凝 血功能、Ch ild - Pugh评分 、主要并发症 、低钠纠正效果及病死率 。结果 　患者低钠血症程度与肝肾功能、凝血功能、 ( ) Ch ild - Pugh分级 、主要并发症 、低钠纠正效果及病死率均具有相关性 P 005, P 00 1 ,仅血清球蛋白在 3 组间 ( ) 差异无显著性 P 005 。结论 　肝硬化失代偿期患者的血清钠水平与其病重程度相关 ,监测血清钠水平可作为 判断肝硬化腹水病情严重程度的重要指标之一 。 【关键词 】肝硬化腹水 ;低钠血症 ; 回顾性分析 【中图分类号 】R5752　　　【文献标识码 】A 　　　【文章编号 】1001 - 5256 (20 10) 02 - 0194 - 03 A retrospective ana ly sis of 145 ca ses w ith decom pen sa tion c irrhosis hypona trem ia 　ZHAN Guo - qing, TAN H ua - bing, ZHU L in, et a l. ( D ep a rtm en t of H ep a tology, P eop le H osp itol, Yuny ang M ed ica l Colleg e, S h iy an, H ubei 442000, Ch ina) A b stract:O bjective　To investigate the relation sh ip between serum sodium level and severity of the disea se in decomp en sated liver cirrho sis p atients. M ethods　145 cirrho sis and a scite s p atients w ith hyponatrem ia were studied retro sp ectively. The p atients were divided into ligh t, moderate and severe hyponatrem ia group s according to their serum sodium levels. Clin ical data including hep atonephric function, b lood coagu lation, Ch ind - Pugh score, m ain comp lication s, effect of cor recting hyponatrem ia and mortality were comp ared among the group s. Results　The degree of hyponatrem ia were related to their hep atonephric function, b lood coagu lation, Ch