抑郁症患者人脸照片诱发的联系性负变研究.pdfVIP

·159· ·论著· 抑郁症患者人脸照片诱发的关联性负变研究 朱跃华1 楼翡璎2 陈 冲2 陈兴时2 吕望强1 【摘要】 目的研究抑郁症患者和健康人的人脸照片诱发的事件相关电位关联性负变(CNV)的 特点。方法应用脑电生理仪和反应时间技术，检测38例抑郁症患者的CNV，并与30名健康对照的 CNV进行比较。结果抑郁症组CNV主要为延迟型(44．74％)，健康对照主要为正常型(66．67％)， CNV分型有统计学差异(Xz=21．32，P0．01)。抑郁症组A点潜伏期为(380±63)ins，健康对照组为 ¨．V，有统计学差异(t=5．13，P0．01)。结论抑郁症患者的CNV波形不规则，潜伏期A点延迟，波幅 B降低。 【关键词】抑郁症人脸照片关联性负变 researchon variationelicitedface in Zhu Preliminary contingentnegative by photosdepression Second Yuehual，幻nn妒n∥，ChenChon92，ChenXingshi2，LUWangqian91．1．PsychiatryDepartment，The MentalHeath School ofJ／nhua，Jinhua321016；2．ShanghaiCenter，Shanghai Hospital JiaotongUniversityof 200030 Medicine，Shanghai 【Abstract】objective：Thecontingentnegativevariation(CNV)，elicitedbydifferentstimulus consistedoftonesandface offamiliar and CNV persons studied．Methods：A paradigms photos strangers，were wasevokedfrom38 and30 depressionpatients healthycontrols(HC)．Results：Thedepressionpatientsmainly the controls normal was showed showed delayedCNV(44．74％)，andhealthy mainly CNV(66．67％)．There differenceinCNV betweenthetwo significant category groups(r=21．32，P0．01)．Depressiongroup showed A decreasedB prolonged A and amplitude(NC：16±51xV，depression：9±6“V，P0．01)．Conclusion：Theprolongedlatency decreasedB ofCNVin deservefurther amplitude depressionpafients study． disorderF