食品BDI-GS评价体系的建立及在酪蛋白评价中的应用.pdfVIP

280 2013, Vol.34, No.03 食品科学 ※营养卫生 食品BDI-GS评价体系的建立及在酪蛋白 评价中的应用 王晓光，王德芝，白佳利，沈 秀，杨 娜，周则卫* (中国医学科学院北京协和医学院放射医学研究所，天津 300 192) 摘  要：目的：通过小鼠实验研究酪蛋白的功效及安全性，建立一种综合评价食品营养、保健功效及安全的BDI- GS新评价体系和方法。方法：对生长期ICR 小鼠，通过12d低营养饲料和掺和酪蛋白饲料培育，对小鼠体质量、 脏器质量/ 系数及其损益指数(BDI)等指标进行考察，并通过BDI 的累积积分(GS)评价酪蛋白的营养、保健功效及 安全性。结果：本研究表明酪蛋白综合营养功效显著，对免疫低下及 Ⅱ型糖尿病有较好的预防保健功效，但对骨 质有一定的负面效应，存在相应安全隐患。结论：本研究建立起一种简便、直观、综合的评价食品营养、保健功 效及安全性的新体系，可以用于多类食品功效及安全的评价。 关键词：损益指数； 酪蛋白；营养；保健；功效安全；评价 Establishment of Food BDI-GS System for Functions and Safety and Application in Casein Assessment * WANG Xiao-guang，WANG De-zhi ，BAI Jia-li ，SHEN Xiu ，YANG Na，ZHOU Ze-wei (Institute of Radiation Medicine, Chinese Academy of Medical Sciences Peking Union Medical College, Tianj in 300 192, China) Abstract ：Objective: In this paper, functions and safety of casein were explored using mouse experiments to establish a novel BDI-GS comprehensive assessment system for nutrition, health promotion and safety of foods. Methods: ICR mice during growth period were fed for 12 days with maize low-nutrient diet and casein-blending diet. Body weight, organ weight, organ index and its benefit-damage index (BDI) of the mice were determined to assess nutrition, health promotion and safety of casein. Results: In the present study, casein possesses significantly comprehensive nutrition, and better health-promoting and preventive effects on immune function and Type II diabetic mellitus. Conclusion: A simple, intuitive and comprehensive system t