综合医院双相情感障碍的诊治-清华大学精神卫生科.pptVIP

* Reference Sachs GS, et al. The expert consensus Guideline series: medication treatment of bipolar disorder. Postgrad Med 2000; Spec N°1: 1-104 * The primary outcome data for the HRSD consisted of 8 weekly observations of 25 subjects receiving divalproex (n = 13) or 安慰剂 (n = 12). At baseline, patients were started on 500 mg per day of divalproex or look-alike 安慰剂, divided into two doses. The medication was rapidly titrated up to 2500 mg/day, as tolerated, to a target serum level of 50–100 lg/dl. The mean percent change in HRSD for patients with bipolar depression treated with divalproex was -