热毒宁联合头孢呋辛钠治疗儿童社区获得性肺炎120例临床观察.DOCVIP

临床医学论文-热毒宁联合头孢呋辛钠治疗儿童社区获得性肺炎120例临床观察 ????????????????????? 作者：陈欣华, 陈草明, 陈毓强 【摘要】? 目的 观察热毒宁联合抗菌药治疗社区获得性肺炎的临床疗效。方法 将240例社区获得性肺炎(CAP)患儿随机分为治疗组和对照组，各120例。对照组为头孢呋辛钠注射液治疗，治疗组为在头孢呋辛钠注射液治疗的基础上，加用热毒宁注射液静脉点滴，疗程10 d.结果 治愈率：治疗组为80 ％ ，对照组为60 ％ ；总有效率：治疗组为96.7 ％ ，对照组为80.8 ％；治疗组疗效明显优于对照组，差异有显著性。在控制体温、呼吸道症状、体征、白细胞恢复天数上，治疗组明显短于对照组。结论 热毒宁联合抗菌药治疗社区获得性肺炎，可以提高疗效。 【关键词】? 热毒宁； 头孢呋辛钠； 儿童社区获得性肺炎 ??? 【Abstract】? Objective To observe the combined Reduning antimicrobial drug treatment of communityacquired pneumonia clinical efficacy. Methods 240 cases of communityacquired pneumonia (CAP) patients were randomly divided into the treatment group and control group, the 120 cases.Cefuroxime sodium for the control group, injection therapy, the treatment group in the treatment of cefuroxime sodium injection on the basis of the added Reduning treatment injection intravenous drip, treatment for 10 days. Results The cure rate: 80 percent for treatment group, control group was 60 %; The total effective rate: 96.7% for the treatment group, 80.8% for the control group; efficacy of the treatment group was superior to the control group, there was a significant difference. In the control of body temperature, respiratory symptoms, symptoms, signs, the number of days on the restoration of leukocytes, the treatment group was significantly shorter than the control group. Conclusion Reduning antimicrobial treatment of joint communityacquired pneumonia can enhance the effectiveness. ??? 【Key words】? reduning;? cefuroxime;? children with Communityacquired pneumonia ?? 儿童社区获得性肺炎(community acquired pneumonia，CAP)是指既往健康儿童在医院外或住院48 h内罹患的感染性肺实质性炎症［1］。是相对于医院内肺炎(hospital acquired pneumonia，HAP)而言的。社区获得性肺炎(CAP)是儿童常见病，也是婴幼儿期死亡的重要原因。全年均可发病，以冬春寒冷季节较多。在我国肺炎患儿占住院儿童总人数的24.5 ％～56.2 ％［2］. 社区获得性肺炎(CAP)主要为细菌，非典型病原体及病毒感染所致［3］。单用或联合应用抗生素疗效越来越不理想。在头孢呋辛注射液治疗基础上，我院采用热毒宁注射液治疗儿童肺炎疗效优于单纯使用头孢呋辛钠。现报道如下： ??? 1? 资料与方法 ??? 1.1? 病例选择 ??? 病例来源于我院儿科2006年1月～2008年12月肺炎患儿住院的病例240例，其中男140例，女100例，年龄2月～10岁，均在发病后24～72 h 内就诊。其临床症状、体征及辅助检查均符合社区获得性肺炎诊断标准［